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  Excerpt:
  ... "It is typically administered by intravenous or intramuscular injection. methoxamine (Vasoxyl). This drug is used prima- rily to increase and maintain" ...
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  by Kim E. Barrett, Susan M. Barman, Scott Boitano, and Heddwen Brooks (Paperback - Jul 24, 2009)
  
  Excerpt:
  ... "a adrenergic receptors Stimulate al receptors Block a receptors methoxamine (Vasoxyl) phenoxybenzamine (" ...
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  Excerpt:
  ... "methoxamine (Vasoxyl) Adrenergic agonist. Adverse effects related Used primarily in critical 20" ...
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  Excerpt:
  ... "the blood pressure maintenance drug methoxamine (7.81, R = CH3, Vasoxyl) gives exclusive 2-O-demethylation (7." ...
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  Clinical Neuroanatomy, 26th Edition
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  Excerpt:
  ... "norepinephrine Tyramine ephedrine amphetamine a Receptors Stimulate a, receptors methoxamine (Vasoxyl) phenylephrine (Neo-Synephrine) Stimulate as receptors Clonidinest P Receptors Stimulate i" ...
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  Excerpt:
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  A Practical Approach to Cardiac Anesthesia
  by Frederick A Hensley, Donald E Martin, and Glenn P Gravlee (Paperback - Aug 1, 2007)
  
  Excerpt:
  ... "Selective agonists 41 (1) Methoxamine(Vasoxyl) 41 (2) phenylephrine (Neo-Synephrine) 41 b. Mixed agonists 42 (1)" ...
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  Mosby's Drug Reference for Health Professions
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  Excerpt:
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  Miller's Anesthesia: Expert Consult Premium Edition - Enhanced Online Features and Print, 2-Volume Set
  by Ronald D. Miller MD, Lars I. Eriksson, Lee A. Fleisher MD, and Jeanine P. Wiener-Kronish MD (Hardcover - May 22, 2009)
  
  Excerpt:
  ... "local anesthetic to prolong sub- arachnoid blockade. In contrast, methoxamine (Vasoxyl) is a much longer-acting drug (30 to 60 minutes).141 In" ...
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  Excerpt:
  ... "phenylephrine (Neo-Synephrine) +++ + - Little at high dose methoxamine (Vasoxyl) ++ + - ephedrine + + + Direct and indirect" ...
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Methoxamine is an α1-adrenergic receptor agonist, similar in structure to phenylephrine and 2,5-DMA. It induces vasoconstriction of skin and splanchnic blood vessels, thereby increasing peripheral vascular resistance and raising mean arterial blood pressure. Because of its hypertensive effects, it may evoke a compensatory reflex bradycardia via the baroreceptors.

See also

phenylephrine
Synephrine

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