medicine: rocuronium bromide

rocuronium bromide description

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Rocuronium (Zemuron, Esmeron) is an aminosteroid non-depolarizing (that is, it does not cause initial stimulation of muscles before weakening them) neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. It is marketed under the trade name of Zemuron in the United States and Esmeron in most other countries.

There is considered to be some risk of allergic reaction to the drug in occasional patients (particularly those with asthma), but a similar incidence of allergic reactions has been observed by using other members of the same drug class (non-depolarizing neuromuscular blocking drugs). The drug is commonly used in modern anaesthesia.

The γ-cyclodextrin derivative sugammadex has been recently introduced as a novel agent to reverse the action of rocuronium.

Trade names

Trade names and prices of rocuronium bromide

Name Information Price* Quantity
       
Generic Rocuronium Bromide Injection 10 mg/mL 10 vials $160 10 vials
Zemuron (12 x 5ml) 10mg/ml 12 vials (rocuronium bromide) $205 12 vials

*) Prices related to some of online drugstores. There are only approximate prices. For some of drugs is needed a prescription.

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