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Jones & Bartlett Clinical Card: Psoriatic Arthritis
by Marc Miller (Pamphlet - Aug. 26, 2009)
Excerpt:
... " Roof scalp: steroids (DermaSmooth 0.0198 hs, or other fluocinolone), Oluxfoam; salicylic acid solutions, tar shampoos, mineral oil Rx of" ...
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medicine: olux foam
olux foam description
Go to trade names and prices
Clobetasol propionate is a corticosteroid used to treat various skin disorders including eczema and psoriasis. clobetasol belongs to Class I (Super Potent) of the corticosteroids, making it one of the most potent available. It comes in ointment and emollient cream presentations. It has very high potency and typically should not be used with occlusive dressings, or for extended continuous use (beyond two weeks). It is also used to treat several auto-immune diseases including alopecia areata, vitiligo and lichen planus (auto immune skin nodules).
Clobetasol propionate is marketed and sold worldwide under numerous names including Clobex, Cosvate (India), temovate (US),Olux, Tenovate, Dermovate, Dermatovate, Butavate, Movate, in China: 丙咪氯苯乳膏 (cream) and 复方丙酸氯倍他索搽剂 (liquid).
Phonetic pronunciation: kloh-BAY-tuh-sall
Forms
Clobetasol propionate ointment USP 0.05%, supplied in Olux 15 g, 30 g, 45 g, and 60 g tubes.Temovate & emollient 0.05%, supplied in 15 g (NDC 0173-0454-01), 30 g (NDC 0173-0454-02) and 60 g (NDC 0173-0454-03) tubes.
Clobetasol propionate foam 0.05%
Clobetasol propionate cream 0.05%
Clobetasol propionate gel 0.05%
Clobestasol propianate spray 0.05%
Dermovate cream and ointment, containing clobetasol propionate 0.05% (UK)
Dermol cream and ointment (NZ)
Possible side effects
Diabetes MellitusOsteoporosis
Acneiform eruptions
Allergic contact dermatitis
Burning sensation
Cracking and fissuring
Cushing's syndrome
Dryness
Erythema
Glaucoma
Folliculitis
Hypertrichosis
Hypopigmentation
Itching
Irritation
Miliaria
Numbness of fingers
Perioral dermatitis
Pruritus
Secondary infection
Skin atrophy
Skin maceration
Stinging
Striae
Telangiectasia
Most important facts about clobetasol Propionate
This medication is to be used as directed by a physician. It is for external use only. Keep out of eyes. When using clobetasol Propionate some of it may be absorbed through the skin and into the bloodstream. Too much absorption may lead to unwanted side effects. To minimize the problem large amounts of clobetasol Propionate should not be used over large areas. Airtight dressings or adhesive bandages are not recommended unless specifically told to by a doctor. Any signs of adverse reactions should be reported to the prescribing physician.
Risk to pregnant women
According to the California Environmental Protection Agency, clobetasol propionate should not be used by pregnant women, or women expecting to become pregnant soon, as studies with rats shows a risk of birth defects:
"Studies in the rat following oral administration at dosage levels up to 50 mg/kg per day revealed that the females exhibited an increase in the number of resorbed embryos and a decrease in the number of living fetuses at the highest dose. Pregnancy: Teratogenic Effects (i.e., possibility of causing abnormailities in fetuses): Pregnancy Category C: clobetasol propionate has not been tested for teratogenicity when applied topically; however, it is absorbed percutaneously, and when administered subcutaneously it was a significant teratogen in both the rabbit and mouse. clobetasol propionate has greater teratogenic potential than steroids that are less potent.There are no adequate and well-controlled studies of the teratogenic effects of clobetasol propionate in pregnant women. temovate Cream and Ointment should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus."
| Name | Information | Price* | Quantity |
| Generic Clobetasol Foam 0.05% | 30 grams (clobetasol) | $32 | 30 grams |
| Olux Foam 0.05% | 100 grams (clobetasol) | $140 | 100 grams |
*) Prices related to some of online drugstores. There are only approximate prices. For some of drugs is needed a prescription.
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