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medicine: nizatidine
nizatidine description
Go to trade names and prices
Nizatidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD). It was developed by Eli Lilly and is marketed under the trade names Tazac and Axid.
Clinical use
Certain preparations of nizatidine are now available over the counter in various countries including the United States. Nizatadine has been used experimentally to control weight gain associated with some antipsychotic medication.
History and development
Nizatidine was developed by Eli Lilly, and was first marketed in 1987. It is considered to be equipotent with ranitidine and differs by the substitution of a thiazole-ring in place of the furan-ring in ranitidine. In September 2000 Eli Lilly announced that they will sell the sales and marketing rights for Axid, to Reliant Pharmaceuticals. Subsequently, Reliant developed the oral solution of axid and got approval by the U.S. Food and Drug Administration (FDA) in May 2004 and started marketing it. However, a year later they sold rights of the axid Oral Solution (including the issued patent US6,930,119 protecting the product) to Braintree Laboratories.
Nizatidine proved to be the last new histamine H2-receptor antagonists introduced prior to the advent of proton pump inhibitors.
| Name | Information | Price* | Quantity |
| Axid 150mg | 30 capsules (nizatidine) | $34 | 30 capsules |
| Axid 300mg | 30 capsules (nizatidine) | $65 | 30 capsules |
| Axid AR 75mg | 50 tablet (nizatidine) | $17 | 50 tablet |
| Axid Oral Solution 15mg/mL | 480 ml (nizatidine) | $333 | 480 ml |
| Nizatidine 150mg | 60 capsule | N/A | |
| Generic Nizatidine 300mg | 30 capsules | $36 | 30 capsules |
*) Prices related to some of online drugstores. There are only approximate prices. For some of drugs is needed a prescription.
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